Biotin and derivatives
Medchemexpress LLC 3H-indolium inner salt (TEA), N-hydroxysuccinimide ester | 1620475-28-6 | 95.0% | 1043.25 | C45H62N4O16S4 | 10 MG
Alexa Fluor 647 NHS ester (TEA) is a far-red, photostable succinimidyl ester dye supplied as the triethylammonium (TEA) salt for covalent labeling of primary amines on proteins, peptides, and amine-modified oligonucleotides. It produces strong fluorescence suitable for fluorescence imaging, flow cytometry, and other fluorescence-based assays. The product is supplied as a blue to dark blue solid and is sensitive to moisture and light.
- Reactive succinimidyl ester for covalent labeling of primary amines.
- Far-red fluorescence compatible with 633-647 nm excitation for imaging and flow cytometry.
- Photostable with high signal intensity for prolonged imaging.
- Suitable for labeling proteins, peptides, and amine-modified oligonucleotides.
- Supplied as a blue to dark blue solid in TEA salt form; store sealed, away from moisture and light.
Medchemexpress LLC Methoxy polyethylene glycol N-hydroxysuccinimide ester | 92451-01-9 | 98.0% | 10MG
Methoxy polyethylene glycol N-hydroxysuccinimide ester, average molecular weight 20,000 Da, is an NHS-activated methoxy-PEG reagent that reacts efficiently with primary amines to form stable amide bonds. It is supplied as a solid for research use and is commonly used for PEGylation of peptides and proteins, linker construction in targeted degraders, and general bioconjugation to improve solubility and pharmacokinetic properties.
- Reacts with primary amines to form stable amide linkages.
- Improves solubility and reduces immunogenicity of conjugates.
- Provides a 20 kDa hydrophilic spacer for linker design.
- Supplied as a high-purity reagent suitable for research applications.
- Compatible with standard coupling and purification workflows.
Medchemexpress LLC PCSK9 Human Biotin 100ug
The PCSK9 protein is an important regulator of plasma cholesterol homeostasis affecting LDL receptor family members such as LDLR and VLDLR It promotes their intracellular degradation and enhances hepatic LDLR degradation through non-proteolytic mechanisms PCSK9 Protein Human (Biotinylated V474I G670E HEK293 Avi) is the recombinant human-derived PCSK9 protein expressed by HEK293 with C-Avi labeled tag and V474I G670E mutation
Medchemexpress LLC Biotin-PEG11-amine | 1418022-42-0 | MFCD21363309 | 99.9% | C34H66N4O13S | 10MG
Biotin-PEG11-amine is a biotin-labeled polyethylene glycol linker with a terminal primary amine, supplied as a solid for research use. It is intended for biotinylation and incorporation into PROTACs or other conjugates, offering improved aqueous solubility and a flexible spacer to reduce steric hindrance during coupling reactions.
- Provides a terminal primary amine for coupling to carboxyl or phosphate groups.
- Contains an 11-unit PEG spacer to improve solubility and flexibility.
- Supports biotin-based affinity capture and detection workflows.
- Supplied as a white to off-white solid with high purity.
- Recommended storage: -20°C protected from light; in solvent, -80°C for long-term storage.
Medchemexpress LLC Sulfo-TAG NHS ester (disodium) | 482618-42-8 | 88.4% | 1185.12 g/mol | C43H39N7Na2O16RuS4 | 1 MG
Sulfo-TAG NHS ester (disodium) is a water-soluble N-hydroxysuccinimide (NHS) ester reagent for covalent labeling of proteins and antibodies via primary amine groups. The reagent contains a ruthenium-based electrochemiluminescent tag that enables sensitive electrochemiluminescence (ECL) detection when conjugated to antibodies. Supplied as a solid for research use; handle and store according to the supplier's SDS and COA.
- Couples to primary amine groups on proteins and antibodies for stable conjugation.
- Enables electrochemiluminescence (ECL) detection when attached to antibodies.
- Water-soluble formulation suitable for aqueous conjugation reactions.
- Provided with storage recommendations to maintain stability.
- Supplied with certificate of analysis (COA) and safety data sheet (SDS) specifying purity and molecular data.
Medchemexpress LLC CD79B Human Biotin 100ug
Recombinant human CD79B (extracellular residues Ala29-Asp159) produced in HEK293 cells and enzymatically biotinylated via an Avi tag. The construct includes a C-terminal His-Avi fusion, is >95% pure, and migrates ~35-45 kDa on SDS-PAGE due to glycosylation. Supplied with storage and reconstitution guidance for use in immobilization and binding assays.
- Site-specific biotinylation for consistent immobilization.
- C-terminal His-Avi tag for purification and controlled biotinylation.
- Mammalian expression preserves native glycosylation and folding.
- High purity suitable for ELISA, SPR/BLI, and flow cytometry.
- Storage and reconstitution recommendations to maintain activity.
Medchemexpress LLC IL-15 Human Biotin 10ug | 10ug
IL-15 protein regulates immune cells stimulates the proliferation of NK cells T cells and B cells and promotes cytokine secretion IL-15 Protein Human (Biotinylated HEK293 Fc-Avi) is the recombinant human-derived IL-15 protein expressed by HEK293 with C-Avi C-hFc labeled tag
Medchemexpress LLC Biotin-C4-amide-C5-NH2 | 151294-96-1 | 97.0% | 314.45 | C14H26N4O2S | 100 MG
Biotin-C4-amide-C5-NH2 is a biotin-based, cleavable linker used to attach cytotoxins to antibodies in the synthesis of antibody-drug conjugates (ADCs). It is supplied as a solid with specified purity and storage instructions for research applications.
- Cleavable ADC linker suitable for ADC construction and biotin labeling.
- Solid, white to off-white appearance.
- Molecular weight 314.45 and formula C14H26N4O2S.
- Purity 97.0%.
- Available in multiple pack sizes, including 100 MG.
- Storage: store at 4°C protected from light; in solution keep at -80°C up to 6 months or -20°C up to 1 month.
Medchemexpress LLC NHS-MMAF | 1404073-19-3 | 97.2% | 943.18 | C49H78N6O12 | 5 MG
NHS-MMAF is an NHS-activated derivative of monomethyl auristatin F (MMAF) designed as a linkerable payload for antibody-drug conjugate research. It acts as a tubulin polymerization inhibitor and is supplied as a solid for laboratory research use.
- High purity suitable for research applications.
- Contains NHS ester for conjugation to amines.
- Potent tubulin polymerization inhibitor.
- Soluble in DMSO; requires ultrasonic treatment and freshly opened DMSO.
- Supplied as a solid; store at -20°C, protect from moisture and light.
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | MFCD21363287 | 98.0% | 884.92 | C38H64N2O21 | 50 MG
Bis-PEG13-NHS ester is a bifunctional PEG-based linker containing N-hydroxysuccinimide (NHS) ester reactive groups that enable efficient amine conjugation; it is used as a cleavable linker in antibody-drug conjugate and PROTAC synthesis and for general bioconjugation chemistry.
- contains N-hydroxysuccinimide (NHS) ester reactive groups.
- functions as a cleavable linker for ADC and PROTAC synthesis.
- molecular formula C38H64N2O21, molecular weight 884.92.
- cas number 2221949-00-2 for unambiguous identification.
- purity 98.0% suitable for research applications.
- available in a 50 MG pack suitable for lab-scale synthesis.
- intended for research use only; not for human or clinical use.
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | MFCD27977502 | 99.9% | C33H56N4O14S | 10MG
Biotin-PEG8-NHS ester is a PEG-based heterobifunctional linker that combines a biotin affinity tag with an N-hydroxysuccinimide (NHS) ester to enable efficient conjugation to primary amines. It is suitable for biotinylation of peptides, proteins, and small molecules, and for use as a linker in targeted protein degradation research and affinity capture workflows.
- Enables efficient conjugation to primary amines via NHS ester chemistry.
- Provides a biotin tag for streptavidin-based capture and detection.
- PEG8 spacer improves solubility and reduces steric hindrance.
- High purity for reproducible conjugation and downstream analysis.
- Suitable for synthesis of linkers and bioconjugates in research applications.
Medchemexpress LLC Sulfo-Cy7.5 NHS ester | 2736437-44-6 | 97.0% | 1104.29 g/mol | C49H48K3N3O16S4 | 10 MG
Sulfo-Cy7.5 NHS ester is a water-soluble, hydrophilic near-infrared cyanine dye functionalized as an N-hydroxysuccinimide (NHS) ester for covalent labeling of primary amines on proteins, peptides, and other biomolecules.
- Near-infrared, water-soluble cyanine dye suitable for NIR imaging and fluorescence labeling.
- Reactive NHS ester for efficient covalent coupling to primary amines under mild conditions.
- Reported molecular weight of 1104.29 g/mol for planning conjugation ratios.
- High reported purity suitable for research applications and labeling workflows.
- Available in small milligram pack sizes for pilot studies and labeling optimization.
- Store sealed, away from moisture and light to maintain stability.